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Endocrinology & Hormones
Thyroid, adrenal, reproductive hormones, and metabolic disorders of glands.
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Latest in Endocrinology & Hormones
Biomarker selection in APMN Prostate Cancer - Himisha Beltran & Joshua Lang
2+ hour, 36+ min ago (964+ words) Himisha Beltran and Joshua Lang discuss biomarker testing for newly diagnosed metastatic prostate cancer. Both agree BRCA2 alterations offer the strongest, most reproducible signal for upfront PARP inhibitor therapy, while genes such as ATM warrant a risk-benefit discussion. Dr. Lang cautions…...
Menopause Hormone Therapy Linked to Improved Mood Symptoms: Study
7+ hour, 52+ min ago (135+ words) USA: Researchers have found in a new study that systemic menopause hormone therapy was associated with significant improvements in depressive mood, irritability, anxiety, and mental exhaustion in a retrospective observational study. The proportion of women with severe mood symptoms declined…...
Satralizumab Shows Clinically Meaningful Improvements in TED
1+ hour, 14+ min ago (202+ words) Adults aged 18 and older with either active, moderate to severe TED or inactive TED were included. Participants were randomized 1:1 to receive subcutaneous satralizumab or placebo. Dosing included a loading period at weeks zero, two and four, followed by every-four-week dosing....
Hormone therapy isn’t a general treatment for depression — but a new menopause study found intriguing mood changes
2+ day, 4+ hour ago (747+ words) Hot flashes may be the menopause symptom everyone recognizes. The feeling many women describe as "I don't feel like myself" can be harder to name — irritability, anxiety, low mood, mental exhaustion and poor sleep arriving in the same stretch of…...
Immune Cells Caught arming the Deadliest Breast Cancer to Spread
1+ day, 17+ hour ago (53+ words) Triple-negative breast cancer is the form of the disease that clinicians fear most. Lacking the three molecular targets — the estrogen receptor, the progesterone receptor and the HER2 protein — that anchor modern targeted therapies, it leaves patients with fewer options and a…...
Semaglutide Shows Promise for Weight Loss and Cooling Inflammation in
1+ day, 18+ hour ago (82+ words) The GLP-1 receptor agonist semaglutide has already reshaped the conversation around obesity medicine, and a new systematic review and meta-analysis published in the International Journal of Obesity adds an important dimension to that story. The analysis examined what happens when…...
Mutational Fingerprints Reveal the Hidden Forces Driving Prostate Cancer
1+ day, 23+ hour ago (671+ words) Prostate cancer is one of the most commonly diagnosed malignancies in men worldwide, yet the processes that sculpt its genome have remained only partially understood....
KIF11 Inhibition Rewires Prostate Cancer Cell Identity to Restore
2+ day, 6+ hour ago (598+ words) One of the most stubborn problems in advanced prostate cancer is that tumors eventually stop listening to the very drugs designed to silence them. Castration-resistant prostate cancer, the lethal form that emerges after androgen-deprivation therapy fails, often escapes by shutting…...