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Drug Discovery & Trials
Targets, biomarkers, AI discovery, and Phases I–III clinical results.
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Latest in Drug Discovery & Trials
Liquid Radioembolic Aims Radiation Directly at Brain Tumors Via Their Own Blood Supply
16+ min ago (662+ words) Mount Sinai and Johnson & Johnson will collaboratively evaluate an investigational liquid radioembolic that combines Iodine-131 with TRUFILL n-BCA to embolize and irradiate brain tumors through their own blood supply, starting with meningiomas....
Labs’ current alignment plans seem terrible — LessWrong
4+ hour, 21+ min ago (1097+ words) Tl;dr: The frontier AI companies’ implicit alignment plans center on rushing towards RSI with something like current models. This plan is (at best) contentious, and many believe it will have catastrophic consequences. Nonetheless, it is the track we are…...
Novo Nordisk Partners with OpenAI for Drug Discovery
1+ hour, 19+ min ago (282+ words) Novo Nordisk intends to apply advanced AI to analyze complex data, improve target identification, and accelerate development of therapies for chronic diseases The deal comes at a time in which AI is rapidly reshaping how biopharma companies discover, develop, and…...
Synthetic Biology in the Open
7+ hour, 19+ min ago (571+ words) Researchers are sharing open source equipment designs, protocols, and code, but what is the synthetic biology community building with them? Synthetic biology is rooted in the idea that engineering principles of standardization, modularity, and abstraction can be applied to biology....
Expanding global access to synthetic biology
18+ hour, 6+ min ago (291+ words) Hanson, A. D. & de Lorenzo, V. ACS Synth. Biol. 12, 1579–1582 (2023). Holland, I. & Davies, J. A. Front. Bioeng. Biotechnol. 8, 571777 (2020). Wang, F. & Zhang, W. J. Biosaf. Biosecur. 1, 22–30 (2019). Cizauskas, C., DeBenedictis, E. & Kelly, P. New Biotechnol. 88, 1–11 (2025). Yang, N., Zhang, H., Han, X., Liu, Z. & Lu, Y. Front....
In the field: Where life sciences’ toughest challenges get solved
9+ hour, 18+ min ago (1168+ words) The usual story of life sciences innovation runs in a straight line: a target is identified, a molecule is designed, a process is developed, scaled and validated, and a therapy reaches patients. What that version leaves out is everything that…...
AI-based drug discovery: Ministry of Science signs MoU with Peptris for collab in AI-based drug discovery and development
10+ hour, 58+ min ago (479+ words) Ministry of Science signs MoU with Peptris for collab in AI-based drug discovery and development The Economic Times...
Mirum’s Phase III EXPAND Study of Livmarli meets goal - The Pharma Letter
6+ hour, 53+ min ago (12+ words) Mirum’s Phase III EXPAND Study of Livmarli meets goal The Pharma Letter...
Rethinking Expression to Accelerate Antibody Discovery
5+ hour, 15+ min ago (83+ words) This webinar will explore integrating the Pfenex Expression Technology® platform directly into the antibody screening workflow. Date: Oct 22, 2026 Time: 11:00 am EDT Complete activation to reserve your place. In this webinar, scientist Russell Coleman, who is director of strain engineering for…...
Dual-targeting siRNAs could treat more complex genetic diseases
4+ hour ago (1072+ words) An innovative bispecific siRNA design hits two genes at once, taking away one of cancer’s tricks for evading treatment. Some might say genetics research is in a rut. Biologists have made incredible biological and therapeutic discoveries over the past several…...