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Lab Techniques
Protocols, reagents, imaging, mass‑spec, and reliable lab practices.
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Springer Nature Honors Standout Editors With 2026 Awards
1+ hour, 13+ min ago (662+ words) Springer Nature has opened the nomination and selection process for its Editor of Distinction Awards 2026, an annual program designed to recognize the editors whose behind-the-scenes judgment keeps the scientific record trustworthy....
AI Translates Light Microscopy Into Electron-Microscope Detail to Speed
1+ hour, 17+ min ago (534+ words) Mapping the wiring of the brain at nanometer resolution has long demanded a punishing trade-off: electron microscopy can reveal every synaptic cleft and organelle, but imaging even a cubic millimeter of neural tissue this way takes months or years of…...
New AI Pipeline Turns Tangled 3D Brain Videos into Clear Neuronal Activity
4+ hour, 21+ min ago (529+ words) Neuroscientists can now record electrical storms of activity from tens of thousands of neurons at once, but a stubborn bottleneck has long stood between the raw data and discovery: turning enormous three-dimensional calcium imaging videos into clean, trustworthy lists of…...
Cryoprotectant-Free Vitrification Leaves Hidden Molecular Marks on Human
4+ hour, 21+ min ago (653+ words) A new study comparing the two main ways of freezing human sperm has found that even when samples look equally healthy under the microscope, the proteins inside them tell a strikingly different story....
MemBrain v2 Brings End-to-End Membrane Analysis to Cryo-Electron Tomography
7+ hour, 11+ min ago (880+ words) Cryо-electron tomography has quietly become one of the most powerful windows into the interior of cells, allowing researchers to peer at the molecular machinery of life in a state close to its native, frozen-hydrated condition....
New Web Tool Lets Researchers Hand-Pick Cells Directly on Spatial Omics
8+ hour, 55+ min ago (573+ words) Spatial biology has been having its breakout decade. Technologies such as imaging mass cytometry, multiplexed immunofluorescence and other multiplexed imaging platforms now allow researchers to measure dozens of biomolecules simultaneously while keeping every cell locked in its original position within…...
A Single Additional Dark-Field Image Reveals Hidden Pathological Details
5+ day, 3+ hour ago (844+ words) New hybrid bright-dark field computational imaging doubles digital pathology resolution, reduces artifacts, and boosts AI cancer screening sensitivity without costly upgrades. Digital Pathology Resolution Enhanced by Hybrid Bright-Dark Field Imaging Hybrid bright-dark field computational imaging enhances digital pathology resolution CHENGDU,…...
SPIFFI Delivers Real-Time Super-Resolution Imaging of Living Cells in a
12+ hour, 18+ min ago (654+ words) Super-resolution fluorescence microscopy has transformed modern cell biology, allowing researchers to peer into structures far smaller than the diffraction limit of light....
HPR-40 DEMS Integration with Metrohm Autolab VIONIC for Real-Time Electrochemical Mass Spectrometry
1+ day, 19+ hour ago (496+ words) Electrochemical research often requires more than current, potential and time data alone. While a potentiostat provides essential control and measurement of the electrochemical experiment, it does not directly identify the gases or volatile species being produced during a reaction. Differential…...
AI helps microscopes find the most informative nanoscale features
2+ day, 11+ hour ago (890+ words) SimuScan uses realistic synthetic data to train AI to identify important nanoscale features and guide atomic force microscopes toward the most informative regions of a sample image: AI-assisted atomic force microscopy identifies tiny surface structures such as nanostructures, DNA assemblies…...